Well longest day so far is 750+ and an average day is 500 or so with a long weekend trip once a month. You gotta learn to lay on the tank and get weight off the wrists. I find a tank bag stuffed with rain gear works great for some padding on the tank. This will take weight off wrists and allow comfortable ride. I am 6' 3" 225 lbs and have survived 53 winters thus far. I don't find pegs to be a problem nor wind protection, which I find to be very good. I use a Shoei helmet and mesh jacket for warmer temps, unless really hot then ditch the jacket. There is a lot of room to move around on the Busa and change positions, which relieves stress points. I rode cruisers for a long time and that dead feeling in my rear would be what made me stop, my rear does not get tired on the busa. I use cortech saddlebags and tail pack that all clip together and attach to bike at 4 points. This makes removal easy. I stop every 60 miles or so to stretch out and get blood flowing. Busa is a great sport tourer, gets 45-50 mpg near speed limit. Again riding position is all important. Back straight lay across tank with elbows on knees or laying on tank bag, which is best. Your neck gets used to being held up and a speed of 80 or so will provide enough wind to hold you up without as much strain. If only running 60-70 mph a tank bag helps a lot. Oh yeah, it corners great and is fast, low maintenance, when it comes time to pass you twist the wrist and are gone.